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Intraoperative use of autologous platelet-rich and platelet-poor plasma for orthopedic surgery patients

February 26, 2010

Intraoperative use of autologous platelet-rich and platelet-poor plasma for orthopedic surgery patientsby Kathleen M. Floryan, William J. Berghoff
AORN Journal, Oct, 2004

Use of autologous platelet concentrate to accelerate soft and hard tissue healing is strongly supported in medical literature. Studies report accelerated bone regeneration, reduced inflammation, decreased blood loss, reduced postoperative narcotic requirements, and improved hard and soft tissue wound healing. (1) Initially, intended for use in patients undergoing total knee arthroplasty (TKA), its use has expanded to:

  • bone fractures
  • laminectomy procedures
  • lateral epicondylitis (ie, tennis elbow)
  • nonunion and bony defects
  • other total joint arthroplasty procedures (eg, hip, shoulder)
  • plantar fasciitis
  • shoulder arthroscopy and distal clavicle resection
  • spinal fusion.

New products and instruments frequently are introduced in the perioperative environment; however, perioperative nurses often are not well versed in the scientific rationale behind use of these novel devices before they are introduced in the OR setting. This was the experience of nursing staff members at Parkview Orthopaedic Hospital, Fort Wayne, Ind, in 2003 when intraoperative use of autologous platelet-rich plasma (PRP) and platelet-poor plasma (PPP) was introduced. The purpose of this article is to help other perioperative nurse who may be introduced to this technology. This article defines autologous PRP and PPP; describes processing and application of PRP and PPP; and reports clinical application outcomes of the use of platelet concentrate for a group of patients who underwent TKA.

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